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    GATE Biochemistry Syllabus 2026 PDF Free Download

    GATE Biochemistry Syllabus 2026 PDF Free Download

    Jalla VenkateshUpdated on 14 Jan 2026, 05:09 PM IST

    GATE Biochemistry Syllabus 2026: IIT Guwahati has published the syllbus for GATE 2026 Biochemistry at gate2026.iitg.ac.in. The GATE 2026 Biochemistry syllabus PDF covers Biochemistry, Microbiology, Genetics, Cellular, Engineering Principles Applied to Biological Systems, Recombinant DNA technology, and more chapters. They can check the direct link for the GATE Biochemistry syllabus 2026 PDF here. The GATE 2026 syllabus includes topics such as the organisation of life, enzyme kinetics, biochemical separation techniques, cell structure and organelles, the Immune System and many more. The authority will conduct the Graduate Aptitude Test in Engineering for postgraduate admission and PSU recruitment. The GATE 2026 exam will be held on February 7, 8, 14 and 15, 2026. Biochemistry is one of the optional papers of GATE Life Sciences. The exam is scheduled on February 7, 2026.
    Direct link to download the GATE 2026 Biochemistry syllabus

    LiveGATE 2026 Result LIVE: Final answer key out at gate2026.iitg.ac.in; scorecard soonMar 18, 2026 | 4:30 AM IST

    The result will include key information such as candidate’s name, registration number, gender, paper name, marks out of 100, score out of 1000, All India Rank (AIR), and qualifying marks.

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    GATE Biochemistry Syllabus 2026 PDF Free Download
    GATE Biochemistry Syllabus 2026

    Along with the exam syllabus, candidates can check the GATE 2026 exam pattern. While preparing for the GATE 2026 Biochemistry exam, candidates must understand the exam pattern, the GATE Biochemistry syllabus and the marking scheme of various important topics. Read the complete article to know about the GATE syllabus for Biochemistry.

    GATE 2026 Biochemistry Syllabus

    Indian Institute of Technology Guwahati has released the GATE Biochemistry syllabus 2026 on the official website, gate2026.iitg.ac.in. Candidates can check the GATE 2026 Biochemistry syllabus in the table below.

    GATE Biochemistry Syllabus 2026 for Engineering Mathematics

    TopicsSub-Topics
    Linear AlgebraMatrices and determinants; Systems of linear equations; Eigenvalues and Eigen vectors.
    CalculusLimits, continuity and differentiability; Partial derivatives, maxima and minima; Sequences and series; Test for convergence
    Differential EquationsLinear and nonlinear first order ODEs, higher order ODEs with constant coefficients; Cauchy’s and Euler’s equations; Laplace transforms.
    Probability and StatisticsMean, median, mode and standard deviation; Random variables; Poisson, normal and binomial distributions; Correlation and regression analysis
    Numerical MethodsSolution of linear and nonlinear algebraic equations; Integration by trapezoidal and Simpson’s rule; Single step method for differential equations.
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    GATE Biochemistry Syllabus 2026 for General Biology

    ChaptersTopics
    BiochemistryBiomolecules - structure and function; Biological membranes - structure, membrane channels and pumps, molecular motors, action potential and transport processes; Basic concepts and regulation of metabolism of carbohydrates, lipids, amino acids and nucleic acids; Photosynthesis, respiration and electron transport chain. Enzymes - Classification, catalytic and regulatory strategies; Enzyme kinetics - Michaelis-Menten equation; Enzyme inhibition - competitive, non-competitive and uncompetitive inhibition.
    MicrobiologyBacterial classification and diversity; Microbial Ecology - microbes in marine, fresh water and terrestrial ecosystems; Microbial interactions; Viruses - structure and classification; Methods in microbiology; Microbial growth and nutrition; Nitrogen fixation; Microbial diseases and host-pathogen interactions; Antibiotics and antimicrobial resistance.
    ImmunologyInnate and adaptive immunity, humoral and cell mediated immunity; Antibody structure and function; Molecular basis of antibody diversity; T cell and B cell development; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organs; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction; Immunization and vaccines
    GATE Previous Year Question Paper's
    Download GATE previous year question papers to understand exam pattern and difficulty level. Practice with these papers to boost your preparation and improve your score.
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    GATE Biochemistry Syllabus 2026 for Genetics, Cellular and Molecular Biology

    ChaptersTopics
    Genetics and Evolutionary BiologyMendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics - transformation, transduction and conjugation; Horizontal gene transfer and transposable elements; Chromosomal variation; Genetic disorders; Population genetics; Epigenetics; Selection and inheritance; Adaptive and neutral evolution; Genetic drift; Species and speciation.
    Cell BiologyProkaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cellcell communication; Cell signalling and signal transduction; Post-translational modifications; Protein trafficking; Cell death and autophagy; Extra-cellular matrix.
    Molecular BiologyMolecular structure of genes and chromosomes; Mutations and mutagenesis; Regulation of gene expression; Nucleic acid - replication, transcription, splicing, translation and their regulatory mechanisms; Non-coding and micro RNA; RNA interference; DNA damage and repair.
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    GATE Biochemistry Syllabus 2026 for Fundamentals of Biological Engineering

    ChaptersTopics
    Engineering Principles Applied to Biological SystemsMaterial and energy balances for reactive and non-reactive systems; Recycle, bypass and purge processes; Stoichiometry of growth and product formation; Degree of reduction, electron balance and theoretical oxygen demand
    Classical Thermodynamics and BioenergeticsLaws of thermodynamics; Solution thermodynamics; Phase equilibria, reaction equilibria; Ligand binding; Membrane potential; Energetics of metabolic pathways, oxidation and reduction reactions
    Transport ProcessesNewtonian and non-Newtonian fluids, fluid flow - laminar and turbulent; Mixing in bioreactors, mixing time; Molecular diffusion and film theory; Oxygen transfer and uptake in bioreactor, kLa and its measurement; Conductive and convective heat transfer, LMTD, overall heat transfer coefficient; Heat exchangers.

    GATE Biochemistry Syllabus 2026 for Bioprocess Engineering and Process Biotechnology

    ChaptersTopics
    Bioreaction EngineeringRate law, zero and first order kinetics; Ideal reactors - batch, mixed flow and plug flow; Enzyme immobilization, diffusion effects - Thiele modulus, effectiveness factor, Damkoehler number; Kinetics of cell growth, substrate utilization and product formation; Structured and unstructured models; Batch, fed-batch and continuous processes; Microbial and enzyme reactors; Optimization and scale up.
    Upstream and Downstream ProcessingMedia formulation and optimization; Sterilization of air and media; Filtration - membrane filtration, ultra filtration; Centrifugation - high speed and ultra; Cell disruption; Principles of chromatography - ion exchange, gel filtration, hydrophobic interaction, affinity, GC, HPLC and FPLC; Extraction, adsorption and drying
    Instrumentation and Process ControlPressure, temperature and flow measurement devices; Valves; First order and second order systems; Feedback and feed forward control; Types of controllers – proportional, derivative and integral control, tuning of controllers

    GATE Biochemistry Syllabus 2026 for Plant, Animal and Microbial Biotechnology

    ChaptersTopics
    PlantsTotipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and cell suspension culture system - methodology, kinetics of growth and nutrient optimization; Production of secondary metabolites; Hairy root culture; Plant products of industrial importance; Artificial seeds; Somaclonal variation; Protoplast, protoplast fusion - somatic hybrid and cybrid; Transgenic plants - direct and indirect methods of gene transfer techniques; Selection marker and reporter gene; Plastid transformation.
    AnimalsCulture media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macrocarrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals; Knock-out and knock-in animals
    MicrobesProduction of biomass and primary/secondary metabolites - Biofuels, bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins and metabolites; Clinical-, food- and industrial- microbiology; Screening strategies for new products.

    GATE Biochemistry Syllabus 2026 for Recombinant DNA Technology and Other Tools in Biotechnology

    ChaptersTopics
    Recombinant DNA technologyRestriction and modification enzymes; Vectors - plasmids, bacteriophage and other viral vectors, cosmids, Ti plasmid, bacterial and yeast artificial chromosomes; Expression vectors; cDNA and genomic DNA library; Gene isolation and cloning, strategies for production of recombinant proteins; Transposons and gene targeting.
    Molecular toolsPolymerase chain reaction; DNA/RNA labelling and sequencing; Southern and northern blotting; In-situ hybridization; DNA fingerprinting, RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; CRISPR-Cas; Biosensing and biosensors.
    Analytical toolsPrinciples of microscopy - light, electron, fluorescent and confocal; Principles of spectroscopy - UV, visible, CD, IR, fluorescence, FT-IR, MS, NMR; Electrophoresis; Microarrays; Enzymatic assays; Immunoassays - ELISA, RIA, immunohistochemistry; immunoblotting; Flow cytometry; Whole genome and ChIP-sequencing.
    Computational toolsBioinformatics resources and search tools; Sequence and structure databases; Sequence analysis - sequence file formats, scoring matrices, alignment, phylogeny; Genomics, proteomics, metabolomics; Gene prediction; Functional annotation; Secondary structure and 3D structure prediction; Knowledge discovery in biochemical databases; Metagenomics; Metabolic engineering and systems biology

    GATE 2026 Exam Pattern For Bio-Chemistry

    The GATE Exam Pattern 2026 has been released on the official website, gate2026.iitg.ac.in. The exam pattern includes information on the number of questions, types of questions, marking scheme, and the duration of the exam. Candidates can check the GATE 2026 exam pattern in the table below.

    GATE Biochemistry 2026 Exam Pattern

    ParticularsDetails

    Examination Mode

    Computer Based Test (Online)

    Duration

    3 Hours

    Number of Papers in GATE 2026

    30 Papers

    Section

    • General Aptitude (GA)

    • Candidate Selected Subject

    Type of Questions

    • Multiple Choice Questions (MCQs)

    • Multiple Select Questions (MSQs)

    • Numerical Answer Type (NAT) Questions

    Design of Questions

    The questions are designed to test the listed abilities

    • Application

    • Analysis

    • Comprehension

    • Recall

    • Synthesis

    Number of Questions

    65 Questions (including 10 questions from General Aptitude)

    Total Marks

    100 Marks

    Marking Scheme

    All of the questions will be worth 1 or 2 marks

    GATE Negative Marking

    Two types of MCQs:

    • MCQs - 1 mark for each correct answer; 1/3 mark will be deducted for every wrong answer.

    • MCQs - 2 marks for each correct answer; 2/3 marks will be deducted for every incorrect response. There are no negative marks for Numerical Answer Type (NAT) questions

    • NO negative marking for MSQ & NAT.

    Frequently Asked Questions (FAQs)

    Q: What is the syllabus for GATE Biochemistry 2026?
    A:

    The syllabus for GATE 2026 Biochemistry includes the Organisation of Life, Enzyme Kinetics, Regulation and Inhibition, Biochemical Separation Techniques, Cell Structure and Organelles, DNA Replication, Transcription and Translation, and the Immune System.

    Q: When should I start preparing for GATE 2026?
    A:

    Starting early is the best option for GATE 2026 preparation. With several months available, early preparation allows candidates ample time for thorough revision and mastering of the syllabus.

    Q: How can I access the detailed GATE Biochemistry Syllabus 2026?
    A:

    Candidates can check the detailed GATE 2026 Biochemistry syllabus on this page.

    Q: Is the GATE Syllabus 2026 Out?
    A:

    Yes, the GATE 2026 syllabus has been released on the official website, gate2026.iitg.ac.in.

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